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  • 产品名称：anti-Cadherin5antibody(CDH5)

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简单介绍：
anti-Cadherin5antibody(CDH5)
详情介绍：
Immunogen Synthetic peptide of human CDH5
Isotype IgG
Purification Antigen affinity purification
Alternative Name CDH5 (CDH5 Antibody Abstract)
Background This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Synonyms: 7B4, CD144
Pathways Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Cadherin 5 (CDH5) antibody (ABIN2426671) Immunohistochemistry of Human gastric cancer using CDH5 Polyclonal Antibody at diluti...