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  • 产品名称:Quetiapin

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  • 产品厂商:TargetMol
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简单介绍:
Quetiapin
详情介绍:
Purpose Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.
Characteristics Tradename: SEROQUEL
Source of Compound: synthetic, ICI-204636, ZD-5077, ZM-204639
Target: Histamine Receptor antagonist,Dopamine Receptor antagonist,5-HT receptor antagonist,AChR antagonist,Adrenergic Receptor antagonist
Receptor: Histamine H1 receptor,Dopamine receptor,5-HT receptor ,Muscarinic AChR,Adrenergic receptor
Status: USAN, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98 %
Formula C21H25N3O2S
Solubility DMSO 36 mg/mL,Water <1 mg="" ml="" <="" td="">
Molecular Weight 383.51 g/mol
CAS-No 111974-69-7
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months