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  • 产品名称：Vandetanib(ZD6474)

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  • 产品厂商：TargetMol
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简单介绍：
Vandetanib(ZD6474)
详情介绍：
Purpose Vandetanib is an orally bioavailable 4-anilinoquinazoline. Vandetanib selectively inhibits the tyrosine kinase activity of vascular endothelial growth factor receptor 2 (VEGFR2), thereby blocking VEGF-stimulated endothelial cell proliferation and migration and reducing tumor vessel permeability. This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that mediates tumor cell proliferation and migration and angiogenesis.
Characteristics Tradename: ZD6474
Source of Compound: synthetic
Target: VEGFR antagonist, EGFR inhibitor
Receptor: VEGFR2/EGFR
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99 %
Formula C22H24BrFN4O2
Solubility DMSO 4 mg/mL,Water <1 mg="" ml="" <="" td="">
Molecular Weight 475.31 g/mol
CAS-No 443913-73-3
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months