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  • 产品名称：Paclitaxel

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  • 产品厂商：TargetMol
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简单介绍：
Paclitaxel
详情介绍：
Purpose Paclitaxel is a novel antineoplastic agent, which was discovered in a screen of extracts of thousands of plants and natural products for antineoplastic activity by a National Cancer Institute program. Alought it functions as a mitotic inhibitor like vinca alkaloids, paclitaxel promotes the polymerization of tubulin instead of inducing the disassembly of microtubules, which inhibits the microtubules disassembly and promotes the formation of excessively stable, dysfunctional microtubules. Paclitaxel has exhibited antitumor activity against a broad spectrum of human cancers, including ovarian, breast, head and neck, and lung cancer, in a large number of studies.
Characteristics Tradename: TAXOL
Source of Compound: Taxus breviofolia, BMS-181339-01
Target: Bcl-2 inhibitor, Microtubule Assosiated inhibitor
Receptor: Bcl-2,Tubulin chain, Microtubule-associated protein
Status: USP, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 100 %
Formula C47H51NO14
Solubility 10 mM in DMSO
Molecular Weight 853.92 g/mol
CAS-No 33069-62-4
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months