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  • 产品名称：Tegaserodmaleate

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简单介绍：
Tegaserodmaleate
详情介绍：
Purpose Tegaserod is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation. Its use was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating and constipation associated with irritable bowel syndrome. On March 30, 2007, the U.S. Food and Drug Administration requested that Novartis withdraw Zelnorm from shelves. The FDA alleges a relationship between prescriptions of the drug and increased risks of heart attack or stroke.
Characteristics Tradename: ZELNORM
Source of Compound: synthetic, HTF-919
Target: 5-HT Receptor antagonist,Serotonin uptake inhibitor
Receptor: 5-HT receptor , Sodium-dependent serotonin transporter
Status: USAN, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98 %
Formula C20H27N5O5
Solubility DMSO:35mg/mL
Molecular Weight 417.46 g/mol
CAS-No 189188-57-6
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months