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  • 产品名称：Bufalin

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简单介绍：
Bufalin
详情介绍：
Purpose Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu, it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in cancer cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway.
Characteristics Target: ATPase inhibitor
Receptor: Na+/K+-ATPase
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98 %
Formula C24H34O4
Solubility 10 mM in DMSO
Molecular Weight 386.52 g/mol
CAS-No 465-21-4
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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image for Bufalin (ABIN4874878) Bufalin