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  • 产品名称：Sulfadoxine

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简单介绍：
Sulfadoxine
详情介绍：
Purpose It is often used in combination with pyrimethamine to treat or prevent malaria. Both drugs are antifolates, they inhibit the production of enzymes involved in the synthesis of folic acid within the parasites. Either drug by itself is only moderately effective in treating malaria, because the parasite Plasmodium falciparum may be able to use exogenous folic acid, i.e. folic acid which is present in the parasite's environment, while in combination, the two substances have a synergistic effect which outbalances that ability.
Characteristics Tradename: FANASIL
Source of Compound: synthetic, RO-4-4393
Target: DHPS inhibitor,DHFR inhibitor
Receptor: DHPS,DHFR-TS
Status: USP, INN, BAN, JAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 97 %
Formula C12H14N4O4S
Solubility Soluble in DMSO > 10 mM
Molecular Weight 310.33 g/mol
CAS-No 2447-57-6
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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