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  • 产品名称:anti-VesicleTransportthroughInteractionwithT-SNAREsHomolog1B(Yeast)(VTI1B)(AA1-

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简单介绍:
anti-VesicleTransportthroughInteractionwithT-SNAREsHomolog1B(Yeast)(VTI1B)(AA1-206)antibody
详情介绍:
Immunogen Recombinant rat vti1b (aa 1-206).
Specificity Specific for vti1b.
Purification antiserum
Alternative Name Vti1b (VTI1B Antibody Abstract)
Application Notes WB: 1 : 1000 (AP staining)
ICC: 1 : 1000
IHC-P: 1 : 250
Restrictions For Research Use only
Format Liquid
Buffer PBS
Handling Advice Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4?°C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20?°C),however, is preferable.
Storage 4 °C/-20 °C
Storage Comment Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
Supplier Images
Western Blotting (WB) image for anti-Vesicle Transport through Interaction with T-SNAREs Homolog 1B (Yeast) (VTI1B) (AA 1-206) antibody (ABIN1742350) dilution: 1 : 1000, sample: crude synaptosomal fraction of rat brain (P2)
Immunocytochemistry (ICC) image for anti-Vesicle Transport through Interaction with T-SNAREs Homolog 1B (Yeast) (VTI1B) (AA 1-206) antibody (ABIN1742350) Immunofluorescence labeling of cultured hippocampal neurons with anti-vti1b (red; dil...
Immunohistochemistry (IHC) image for anti-Vesicle Transport through Interaction with T-SNAREs Homolog 1B (Yeast) (VTI1B) (AA 1-206) antibody (ABIN1742350) Indirect immunostaining of PFA fixed mouse cerebellum section (dilution 1?:?200; red)...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Vesicle Transport through Interaction with T-SNAREs Homolog 1B (Yeast) (VTI1B) (AA 1-206) antibody (ABIN1742350) Immunostaining of paraffin embedded sections from mouse cerebellum (dilution 1 : 250)...
Product cited in: Bhat, Friedmann, Kn?rck, Hoxha, Leidinger, Backes, Meese, Keller, Rettig, Hoth, Qu, Schwarz: "Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes." in: Biochimica et biophysica acta, Vol. 1863, Issue 7 Pt A, pp. 1653-64, 2016 (PubMed).

Golebiewska, Harper, Williams, Savage, Goggs, Fischer von Mollard, Poole: "Syntaxin 8 regulates platelet dense granule secretion, aggregation, and thrombus stability." in: The Journal of biological chemistry, Vol. 290, Issue 3, pp. 1536-45, 2015 (PubMed).

Ramirez, Khvotchev, Trauterman, Kavalali: "Vti1a identifies a vesicle pool that preferentially recycles at rest and maintains spontaneous neurotransmission." in: Neuron, Vol. 73, Issue 1, pp. 121-34, 2012 (PubMed).

Offenh?user, Lei, Roy, Collins, Stow, Murray: "Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 6, pp. 762-73, 2011 (PubMed).

Qu, Pattu, Junker, Schwarz, Bhat, Kummerow, Marshall, Matti, Neumann, Pfreundschuh, Becherer, Rieger, Rettig, Hoth: "Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 12, pp. 6894-904, 2011 (PubMed).

Fraldi, Annunziata, Lombardi, Kaiser, Medina, Spampanato, Fedele, Polishchuk, Sorrentino, Simons, Ballabio: "Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders." in: The EMBO journal, Vol. 29, Issue 21, pp. 3607-20, 2010 (PubMed).