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  • 产品名称：anti-HOMER1antibody(HomerHomolog1(Drosophila))(AA175-186)

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  • 产品厂商：SYSY
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简单介绍：
anti-HOMER1antibody(HomerHomolog1(Drosophila))(AA175-186)
详情介绍：
Immunogen Synthetic peptide (aa 175-186 of rodent homer 1a) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.
Specificity Specific for homer 1a.
Purification Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
Alternative Name Homer 1a (HOMER1 Antibody Abstract)
Background Synonyms: VesL 1, Syn47
Pathways Skeletal Muscle Fiber Development
Application Notes WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: not tested yet
IHC: not tested yet
Restrictions For Research Use only
Format Lyophilized
Reconstitution For reconstitution add 50 μL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
Buffer PBS
Handling Advice Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4?°C for prolonged periods (i.e. several weeks), is not recommended.
Storage -20 °C
Storage Comment Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
Supplier Images
Western Blotting (WB) image for anti-Homer Homolog 1 (Drosophila) (HOMER1) (AA 175-186) antibody (ABIN1742337) dilution: 1 : 1000, sample: crude synaptosomal fraction of rat brain (P2)
Product cited in: Banerjee, Luong, Ho, Saib, Ploski: "Overexpression of Homer1a in the basal and lateral amygdala impairs fear conditioning and induces an autism-like social impairment." in: Molecular autism, Vol. 7, pp. 16, 2016 (PubMed).

Schafer, Heller, Gunner, Heller, Gordon, Hammond, Wolf, Jung, Stevens: "Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression." in: eLife, Vol. 5, 2016 (PubMed).

Tao-Cheng, Thein, Yang, Reese, Gallant: "Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation." in: Neuroscience, Vol. 266, pp. 80-90, 2014 (PubMed).