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  • 产品名称:anti-Neurexin1/2/3(NRXN1/2/3)(AA1328-1421)antibody

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简单介绍:
anti-Neurexin1/2/3(NRXN1/2/3)(AA1328-1421)antibody
详情介绍:
Immunogen Recombinant protein (aa 1328-1421) of rat alpha-neurexin 1.
Specificity Specific for neurexin 1. The epitope is present in alpha- and beta-neurexin 1.
Purification Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
Alternative Name Neurexin 1/2/3
Application Notes WB: 1 : 500 up to 1 : 1000 (AP staining)
IP: not tested yet
ICC: not recommended
IHC: not recommended
Comment

WB: Unboiled samples yield stronger signals.

Restrictions For Research Use only
Format Lyophilized
Reconstitution For reconstitution add 50 μL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
Buffer PBS
Handling Advice Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4?°C for prolonged periods (i.e. several weeks), is not recommended.
Storage -20 °C
Storage Comment Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
Supplier Images
Western Blotting (WB) image for anti-Neurexin 1/2/3 (NRXN1/2/3) (AA 1328-1421) antibody (ABIN1742366) dilution: 1 : 1000, sample: rat brain honogenate (unboiled sample)
Product cited in: Bot, Schweizer, Ben Halima, Fraering: "Processing of the synaptic cell adhesion molecule neurexin-3beta by Alzheimer disease alpha- and gamma-secretases." in: The Journal of biological chemistry, Vol. 286, Issue 4, pp. 2762-73, 2011 (PubMed).

Lim, Kwon, Lee, Moon, Jeong, Park, Kim, Park, Lee, Ryu, Yu, Chung, Kim, Myung, Lee: "Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn." in: The EMBO journal, Vol. 28, Issue 22, pp. 3564-78, 2009 (PubMed).