anti-Abeta-pE11antibody 抗体网

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产品名称：anti-Abeta-pE11antibody
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产品厂商：SYSY
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简单介绍：

anti-Abeta-pE11antibody

详情介绍：

Product details
Product details
Immunogen	Synthetic peptide pyr-EVHHQK coupled to key-hole limpet hemocyanin via an added C-terminal cysteine residue.
Specificity	Specific for Abeta-pE11.
Purification	Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Target details
Target details
Background	Synonyms: pyro-Glu Abeta, pE-Abeta, pGlu-Abeta, Abeta(11(pE)-40/42)

Application Details
Application Details
Application Notes	WB: 1 : 1000 IP: not tested yet ICC: not tested yet IHC: 1 : 200 IHC-P: 1 : 100
Comment	WB: Detects purified Abeta-pE11. complex samples like brain extracts not tested yet. ELISA: Suitable as detector antibody.
Restrictions	For Research Use only

Handling
Handling
Format	Lyophilized
Reconstitution	For reconstitution add 50 μL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
Buffer	PBS
Handling Advice	Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4?°C for prolonged periods (i.e. several weeks), is not recommended.
Storage	-20 °C
Storage Comment	Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

Images
Images
Supplier Images	Detection of different synthetic Abeta species with mouse anti-Abeta-pE11 (dilution 1... anti-Abeta-pE11 antibody (Image 2) Immunostaining of a cryo-section from an Alzheimer's patient with anti-Abeta-pE11 (di... Immunostaining of paraffin embedded brain section from an Alzheimer's patient (diluti... Images for product: anti-Abeta-pE11 antibody Detection of different synthetic Abeta species with mouse anti-Abeta-pE11 (dilution 1 : 1000) and a commercially available monoclonal anti-Abeta antibody. Peptides have been resolved by denaturing 16.5 % Schaegger PAGE. anti-Abeta-pE11 antibody (Image 2) Immunostaining of a cryo-section from an Alzheimer's patient with anti-Abeta-pE11 (dilution 1 : 200; red) counterstained with digoxiginated mouse anti-Abeta-pE3 (cat. no. 218 011; blue) and a commercially available biotinylated generic mouse Abeta antibody (green). Immunostaining of paraffin embedded brain section from an Alzheimer's patient (dilution 1 : 100). Immunoreactivity in amyloid plaques was revealed using diaminobenzidine as chromagen. Nuclei were counterstained with haematoxylin (blue).

References
References
Product cited in:	Kalimo, Lalowski, Bogdanovic, Philipson, Bird, Nochlin, Schellenberg, Brundin, Olofsson, Soliymani, Baumann, Wirths, Bayer, Nilsson, Basun, Lannfelt, Ingelsson: "The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ." in: Acta neuropathologica communications, Vol. 1, Issue 1, pp. 60, 2013 (PubMed).