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Characteristics
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PubChem CID: 73051434
Molecular Formula: C₂₄H₂₃N₅O₂
Cell Premeable: Yes Salt form: No CB5083 is a potent, ATP-competitive, D2-selective, p97 inhibitor (IC₅₀ = 11 nM). In xenograft models, CB-5083 causes modulation of key p97-related pathways, induces apoptosis, and has antitumor activity in a broad range of both hematological and solid tumor models. Smiles: CC1=CC2=C(C=CC=C2N1C3=NC4=C(COCC4)C(=N3)NCC5=CC=CC=C5)C(=O)N InChi: InChI=1S/C24H23N5O2/c1-15-12-18-17(22(25)30)8-5-9-21(18)29(15)24-27-20-10-11-31-14-19(20)23(28-24)26-13-16-6-3-2-4-7-16/h2-9,12H,10-11,13-14H2,1H3,(H2,25,30)(H,26,27,28) Inchi Key: RDALZZCKQFLGJP-UHFFFAOYSA-N
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