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  • 产品名称：Lasofoxifenetartrate

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  • 产品厂商：Biovision
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简单介绍：
Lasofoxifenetartrate
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Characteristics

PubChem CID: 3081919
Molecular Formula: C₂₈H₃₁NO₂.C₄H₆O₆
Cell Premeable: Yes

Salt form: No

Lasofoxifene is a unique, non-steroidal selective estrogen receptor modulator (SERM). It selectively binds to human ERα with an IC₅₀ value of 1.5 nM and inhibits bone loss in ovariectomized rats. Has potential use in treating breast cancer.

Smiles: C1CCN(C1)CCOC2=CC=C(C=C2)C3C(CCC4=C3C=CC(=C4)O)C5=CC=CC=C5.C(C(C(=O)O)O)(C(=O)O)O

InChi: InChI=1S/C28H31NO2.C4H6O6/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29,5-1(3(7)8)2(6)4(9)10/h1-3,6-9,11-13,15,20,26,28,30H,4-5,10,14,16-19H2,1-2,5-6H,(H,7,8)(H,9,10)/t26-,28+,1-,2-/m10/s1

Inchi Key: INEHJXCWEVNEDZ-LUDNRVPPSA-N
Purity ≥ 98 % by HPLC
Chemical Name (5R,6S)-5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol, (2S,3S)-2,3-dihydroxybutanedioate; CP-336,156
Formula C₂₈H₃₁NO₂.C₄H₆O₆
Permeability Cell-permeable
Background Synonyms: (5R,6S)-5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol, (2S,3S)-2,3-dihydroxybutanedioate, CP-336,156
Molecular Weight 563.6 g/mol
CAS-No 190791-29-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months