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  • 产品名称：(S)-H-1152dihydrochloride

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  • 产品厂商：Biovision
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简单介绍：
(S)-H-1152dihydrochloride
详情介绍：
Purpose A potent, specific ATP-competitive rho-kinase (ROCK) inhibitor
Characteristics H-1152 dihydrochloride is a potent, cell permeable, specific, ATP-competitive inhibitor of Rho-kinase (ROCK) (Ki = 1.6 nM). H-1152 poorly inhibits PKA, PKC, and myosin light chain kinase (Ki = 0.63, 9.27, and 10.1 μM, respectively).
Purity ≥ 98 % by HPLC
Chemical Name (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride
Formula C₁₆H₂₁N₃O₂S.2HCl
Permeability Cell-permeable
Solubility DMSO (>15 mg/ml)
Molecular Weight 392.34 g/mol
CAS-No 451462-58-1
Restrictions For Research Use only
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 36 months