|
Purpose
|
An adenylate cyclase inhibitor
|
|
Characteristics
|
2’, 5’- Dideoxyadenosine is a cell-permeable inhibitor of adenylate cyclase (IC₅₀ = 2.7 µM). Inhibits growth and causes cell differentiation (1.5 µM) in K562 cells.
|
|
Purity
|
≥ 98 % by HPLC
|
|
Chemical Name
|
2',5'-Dideoxy-D-adenosine; 2',5'-DDA
|
|
Formula
|
C₁₀H₁₃N₅O₂
|
|
Permeability
|
Cell-permeable
|
|
Solubility
|
H₂O (~20 mg/ml, warming) or DMSO (~ 30 mg/ml)
|
