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  • 产品名称：AM-095

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  • 产品厂商：Biovision
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AM-095
详情介绍：
Purpose A potent LPA1 receptor antagonist
Characteristics AM-095 is a potent LPA1 receptor antagonist with IC₅₀ values of 0.98 and 0.73 μM for recombinant human and mouse LPA1, respectively. In functional assays, AM-095 inhibitsLPA-driven chemotaxis of CHO cells overexpressing mouse LPA₁ (IC₅₀ = 778 nM) and human A2058 melanoma cells (IC₅₀ = 233 nM).
Purity ≥ 98 % by HPLC
Chemical Name 2-[4-[4-[3-methyl-4-[[(1R)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid
Formula C₂₇H₂₄N₂O₅
Permeability Cell-permeable
Solubility DMSO (>5 mg/ml)
Molecular Weight 456.49 g/mol
CAS-No 1228690-36-5
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months