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Purpose
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A histone demethylase (HDM) inhibitor and an epigenetic modulator
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Characteristics
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AS8351 is a histone demethylase (HDM) inhibitor and an epigenetic modulator. In combination with eight other small molecules (called 9C), AS8351 enables conversion of human fibroblasts into cardiomyocyte-like cells.
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Purity
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≥ 98 % by TLC
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Chemical Name
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2-Hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone; NSC-51355
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Formula
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C₁₇H₁₃N₃O₂
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Permeability
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Cell-permeable
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Solubility
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DMSO
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