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  • 产品名称：AR-42(HDAC-42)

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  • 产品厂商：Biovision
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简单介绍：
AR-42(HDAC-42)
详情介绍：
Purpose A potent HDAC inhibitor
Characteristics AR-42 is a potent histone deacetylase inhibitor (HDACi). It induces growth inhibition, cell- cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 also promotes hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21 and exhibits in vitro and ex vivo biologic activity against malignant mast cells.
Purity ≥ 98 % by HPLC
Chemical Name S)-N-hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide
Formula C₁₈H₂₀N₂O₃
Permeability Cell-permeable
Solubility DMSO (~ 20 mg/ml) or EtOH (~ 20 mg/ml
Molecular Weight 312.36 g/mol
CAS-No 935881-37-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months