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Purpose
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A potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK)
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Characteristics
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AVL-292 is a potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK) (IC₅₀ = 0. 5 nM) with potential antineoplastic activity.
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Purity
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≥ 98 % by HPLC
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Chemical Name
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N-(3-((5-fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide; CC-292
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Formula
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C₂₂H₂₂FN₅O₃
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Permeability
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Cell-permeable
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Solubility
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DMSO (>50 mg/ml)
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