|
Purpose
|
A potent and selective protease-activated receptor 2 (PAR2) agonist
|
|
Characteristics
|
AC 55541 is a potent and selective protease-activated receptor 2 (PAR2) agonist (pEC₅₀ = 6.7) that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation.
|
|
Purity
|
≥ 98 % by HPLC
|
|
Chemical Name
|
2E)-2-[1-(3-Bromophenyl)ethylidene] α-(benzoylamino)-3,4-dihydro-4-oxo-1-phthalazineacetic acid hydrazide
|
|
Formula
|
C₂₅H₂₀BrN₅O₃
|
|
Permeability
|
Cell-permeable
|
|
Solubility
|
DMSO (~ 25 mg/ml)
|
