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  • 产品名称：AZ10417808

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  • 产品厂商：Biovision
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简单介绍：
AZ10417808
详情介绍：
Purpose A non-peptidic caspase-3 inhibitor
Characteristics AZ10417808 is a selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC₅₀ = 14.9 μM).
Purity ≥ 98 % by HPLC
Chemical Name 2-(3,4-dichloroanilino)-6-nitro-4-oxo-N-prop-2-enyl-1H-quinazoline-8-carboxamide
Formula C₁₈H₁₃Cl₂N₅O₄
Permeability Cell-permeable
Solubility DMSO (~ 10 mg/ml)
Molecular Weight 434.23 g/mol
CAS-No 331645-84-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months