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PubChem CID: 23582824
Molecular Formula: C₁₈H₁₁N₃O₂S
Cell Premeable: Yes GSK-1059615 is a potent, reversible, ATP-competitive inhibitor of PI3Kα (IC₅₀ = 2 nM). It inhibits proliferation in BT474 cells and attenuates MAPK signaling. Smiles: C1=CC2=NC=CC(=C2C=C1C=C3C(=O)NC(=O)S3)C4=CC=NC=C4 InChi: InChI=1S/C18H11N3O2S/c22-17-16(24-18(23)21-17)10-11-1-2-15-14(9-11)13(5-8-20-15)12-3-6-19-7-4-12/h1-10H,(H,21,22,23)/b16-10- Inchi Key: QDITZBLZQQZVEE-YBEGLDIGSA-N
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