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  • 产品名称：EnfuvirtideAcetate

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  • 产品厂商：Biovision
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简单介绍：
EnfuvirtideAcetate
详情介绍：
Purpose Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS.
Sequence Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2. CH3CO2H
Characteristics White to off-white solid
Molecular formular: C206H305N51O66
Purity ≥ 98 %
Chemical Name Fuzeon; T20; Pentafuside
Formula C₂₀₆H₃₀₅N₅₁O₆₆
Permeability Not-permeable
Molecular Weight 4552.62 g/mol
CAS-No 914454-00-5
Comment

Synonyms:
Fuzeon, T20, Pentafuside
Enfuvirtide is an antiretroviral drug used in combination therapy for the treatment of HIV-1/AIDS. It binds to the first heptad-repeat (HR1) in the gp41 subunit of the viral envelope glycoprotein and prevents the conformational changes required for the fusion of viral and cellular membranes. It works by disrupting the HIV-1 molecular machinery at the final stage of fusion with the target cell, preventing uninfected cells from becoming infected
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months