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  • 产品名称:Nec-1s

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Nec-1s
详情介绍:
Characteristics A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (ABIN629212) (EC50 = 210 nM versus EC50 = 490 nM), as well as showing no nonspecific cytotoxicity at high concentrations (ca. 100 mM). More useful for in-cell and in vivo experiments compared to Nec-1.
Purity ≥ 96 % by TLC and LC-MS
Chemical Name 5-((7-Cl-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione); 7-Cl-O-Nec-1
Formula C₁₃H₁₂ClN₃O₂
Permeability Cell-permeable
Molecular Weight 277.71 g/mol
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
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