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  • 产品名称：EPZ-6438

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  • 产品厂商：Biovision
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EPZ-6438
详情介绍：
Characteristics A potent and selective inhibitor of histone methyltransferase EZH2. EPZ-6438 specifically inhibits cellular H3K27 methylation leading to selective apoptotic killing of SMARCB1 mutant MRT cells. It also induces neuronal differentiation and cell cycle inhibition while suppressing expression of Hedgehog (Hh) pathway genes.
Purity ≥ 98 % by HPLC
Chemical Name N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide; E-7438
Formula C₃₄H₄₄N₄O₄
Permeability Cell-permeable
Molecular Weight 572.74 g/mol
CAS-No 1403254-99-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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