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Characteristics
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A biotinylated derivative of the tetrapeptide inhibitor ASTD-FMK, which acts as a competitive inhibitor for the cleavage site of pro-EMAP II (Endothelial monocyte-activating polypeptide). EMAPII, which is a proinflammatory cytokine and a chemoattractant for monocytes, is specifically processed and released upon the induction of apoptosis in cultured cells.
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