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Characteristics
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KEY FEATURES & APPLICATIONS: Water-soluble Adds a 5-atom spacer arm (8.1 A°) to minimize steric hindrance The spacer is cleavable at the disulfide bond with reducing agent, such as DTT, TCEP, etc. Commonly used to convert primary amines into sulfhydryl groups in a one-step process is called thiolation Amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides Useful RNA-protein crosslinking reagent.
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