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Characteristics
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KEY FEATURES: Amine reactive Sulfo-NHS ester that crosslinks efficiently with primary amine-containing molecules Has a maleimide functional group that can be utilized to react specifically with cysteines or sulfhydryl (-SH) groups Water-soluble, can be used under physiologic conditions Has a spacer arm length of 8.3 A° (9 atom) Unlike other maleimide-activated antibodies, those made with Sulfo-SMCC crosslinkers are often more stable, due to the inductive stabilizing effects of the cyclohexyl ring moeityAPPLICATIONS: Routinely used to prepare hapten-carrier protein and antibody-enzyme conjugates, such as HRP conjugation. Wide range of uses for both small molecule reactions and large biomolecule applications.
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