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  • 产品名称:IWP-2

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  • 产品厂商:Biovision
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简单介绍:
IWP-2
详情介绍:
Characteristics Cell-permeable. Acts as an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC50 = 27 nM) by inhibition of the O-acyltransferase Porcn. Porcn is a member of the membrane-bound O-acyltransferase (MBOAT) family, which adds a palmitoyl group to Wnt proteins that is essential to their signaling ability and is required for Wnt secretion.
Purity ≥ 98 % by TLC
Chemical Name N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Formula C₂₂H₁₈N₄O₃S₃
Permeability Cell-permeable
Molecular Weight 466.6 g/mol
CAS-No 686770-61-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 48 months
Supplier Images
 image for IWP-2 (ABIN809556) IWP-2