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  • 产品名称：HPI-1

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  • 产品厂商：Biovision
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简单介绍：
HPI-1
详情介绍：
Characteristics HPI-1 is a Hedgehog pathway inhibitor acting downstream of Smo and independently of PKA, PI3K and MAPK. It can suppress Hh pathway activation induced by loss of Su(fu) or Gli overexpression. Inhibits both endogenous and exogenous Gli1/Gli2 activity. IC50's range from 0.2 to 6 µM for various cell-based assays.
Purity ≥ 98 % by TLC
Chemical Name 2-Methoxyethyl 1,4,5,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7-(-(2-methoxyphenyl)-2-methyl-5-oxo-3-quinolinecarboxylate
Formula C₂₇H₂₉NO₆ • XH₂O
Permeability Cell-permeable
Molecular Weight 463.52 g/mol
CAS-No 599150-20-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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image for HPI-1 (ABIN1685833) HPI-1