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  • 产品名称:EPZ004777

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  • 产品厂商:Biovision
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简单介绍:
EPZ004777
详情介绍:
Characteristics A potent and selective DOT1L inhibitor. Treatment of leukemic cells with EPZ004777 results in selective killing of those cells bearing the MLL (mixed lineage leukemia) gene translocation, with little effect on non-MLL-translocated cells.
Purity ≥ 98 % by HPLC
Chemical Name 1-(3-((((2R,3S,4R,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea
Formula C₂₈H₄₁N₇O₄
Permeability Cell-permeable
Molecular Weight 539.67 g/mol
CAS-No 1338466-77-5
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
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 image for EPZ004777 (ABIN1685779) EPZ004777