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  • 产品名称：A771726

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  • 产品厂商：Biovision
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简单介绍：
A771726
详情介绍：
Characteristics Physiologically active metabolite of the immunosuppressive drug leflunomide. Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kappaB activation in a dose- and time-dependent manner. Also inhibits the activity of COX-2 in vitro and in vivo.
Purity ≥ 98 % by HPLC
Chemical Name N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
Formula C₁₂H₉F₃N₂O₂
Permeability Cell-permeable
Molecular Weight 270.21 g/mol
CAS-No 108605-62-5
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 48 months
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image for A77 1726 (ABIN809578) A77 1726