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  • 产品名称：Chidamide

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  • 产品厂商：Biovision
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简单介绍：
Chidamide
详情介绍：
Characteristics Cell-permeable. A new benzamide class of histone deacetylase (HDAC) inhibitor with marked anti-tumor activity. It increases histone H3 acetylation levels in LoVo and HT29 colon cancer cells at concentrations as low as 4 µM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells.
Purity ≥ 98 %
Chemical Name N-​(2-​amino-​5-​fluorophenyl)-​4-​[[[1-​oxo-​3-​(3-​pyridinyl)-​2-​propen-​1-​yl]amino]methyl]-​benzamide
Formula C₂₂H₁₉FN₄O₂
Permeability Cell-permeable
Molecular Weight 390.41 g/mol
CAS-No 743420-02-2
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and mositure
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for Chidamide (ABIN1685543) Chidamide