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Characteristics
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A microtubule inhibitor, inhibits mitosis. Disrupts microtubules by binding to beta-tubulin and preventing formation of one of the two interchain disulfide linkages, thus inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex. Arrests the cell cycle at G2/M phase. Also inhibits autophagosome-lysosome fusion.
Synonyms: 5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbonic acid, methyl ester
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