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Characteristics
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Retinoic acid is a metabolite of vitamin A that acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). RAR and RXR heterodimerize and act as ligand-dependent transcriptional regulators, with roles in development, reproduction, immunity, organogenesis, and cancer. Retinoic acid primes embryonic stem cells to become neurons.
Synonyms: ATRA, Tretinoin, NSC 122758, Vitamin A Acid, all-trans Retinoic Acid, NSC 122578
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