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  • 产品名称：Emetinedihydrochloride

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  • 产品厂商：Biovision
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简单介绍：
Emetinedihydrochloride
详情介绍：
Characteristics A bitter-tasting crystalline alkaloid,derived from ipecac root and used in the treatment of amebiasis and as an emetic.Irreversibly blocks protein synthesis by inhibiting the movement of ribosome along the mRNA. Induces hypotension by blocking adrenoreceptors. Inhibits DNA replication in the early S phase. Inhibits HIF-1 activation by hypoxia. Induces apoptosis in leukemia cells. Also, selectively inhibits multiple glioblastoma (GBM) stem cells-enriched cultures.
Purity ≥ 98 % by titration
Chemical Name 2S,3R,11bS)-2-{[(1R)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline
Formula C₂₉H₄₀N₂O₄•2HCl
Permeability Not-permeable
Molecular Weight 553.56 g/mol
CAS-No 316-42-7
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage 4 °C
Expiry Date 48 months
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image for Emetine dihydrochloride (ABIN809572) Emetine dihydrochloride