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  • 产品名称：Itraconazole

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  • 产品厂商：Biovision
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简单介绍：
Itraconazole
详情介绍：
Characteristics A synthetic broad-spectrum triazole antifungal agent with the mode of action being through Inhibition of cytochrome P450 dependent enzymes including 14alpha-demethylase. Recently, it has been shown that Itraconazole inhibits Hedgehog (Hh) signaling pathway activity (IC50 = 0.8 µM) as well as blocks the VEGFR2 glycosylation, trafficking, and signaling in endothelial cells.
Purity ≥ 97 %
Chemical Name (2R,4S)-rel-1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one; Oriconazole, R51211, Sporanox
Formula C₃₅H₃₈Cl₂N₈O₄
Permeability Not-permeable
Molecular Weight 705.63 g/mol
CAS-No 84625-61-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 60 months
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image for Itraconazole (ABIN809602) Itraconazole