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  • 产品名称：Leflunomide

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  • 产品厂商：Biovision
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简单介绍：
Leflunomide
详情介绍：
Characteristics Cell-permeable. An immunosuppressive agent. Inhibits T and B cell responses in vivo. Inhibitor of tyrosine phosphorylation (tyrosine kinase inhibitor), of dihydroorotate dehydrogenase, an enzyme for de novo pyrimidine synthesis, of TNF-dependent NF-kappaB activation, and of COX-2. The physiological activity of leflunomide is attributed mainly to its metabolite A77 1726.
Purity ≥ 98 % by HPLC
Chemical Name 5-Methylisoxazole-4-(4-trifluoromethylcarboxanilide), N-(4-Trifluoromethylphenyl)-5-methylisoxazol-4-carboxamide; HWA486,
Formula C₁₂H₉F₃N₂O₂
Permeability Cell-permeable
Molecular Weight 270.21 g/mol
CAS-No 75706-12-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 48 months
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