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Characteristics
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A structural analog of EUK 8 and EUK 134 with significantly reduced activity. Acts as a synthetic catalytic scavenger of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity. Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 with an IC50 value of 2.0 µm.
Synonyms: (acetato-kappaO)[[2,2'-[1,2-ethanediylbis[(nitrilo-kappaN)methylidyne]]bis[3,5-dimethoxyphenolato-kappaO]](2-)]-manganese
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