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  • 产品名称：GANT61

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  • 产品厂商：Biovision
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简单介绍：
GANT61
详情介绍：
Characteristics Cell-permeable. A Hedgehog (Hh) signaling pathway antagonist. Inhibits Hh signaling downstream of Smo and Sufu at the level of Gli (IC50 = 5 µM). GANT61 has also been shown to inhibit the in vitro proliferation of PANC1 and 22Rv1 cells which have elevated GLi11 levels and prevent the development of 22Rv1 tumors in mice.
Purity ≥ 98 % by HPLC
Chemical Name 2,​2'-​[[dihydro-​2-​(4-​pyridinyl)-​1,​3(2H,​4H)-​pyrimidinediyl]bis(methylene)]bis(N,​N-​dimethyl-​benzenamine); NSC 136476
Formula C₂₇H₃₅N₅
Permeability Cell-permeable
Molecular Weight 429.6 g/mol
CAS-No 500579-04-4
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
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image for GANT61 (ABIN629266) GANT61