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  • 产品名称:EZSolution™Torin1

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  • 产品厂商:Biovision
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EZSolution™Torin1
详情介绍:
Brand EZSolution™
Characteristics A potent, selective and ATP-competitive mTOR inhibitor, with IC50values of 2 and 10 nM for mTORC1 and mTORC2 respectively, Torin1 displays 1000-fold selectivity for mTOR over PI3K (EC50 = 1800 nM) and exhibits 100-fold binding selectivity relative to 450 other protein kinases.
Purity ≥ 98 % by HPLC
Chemical Name 1-[4-[4-(1-Oxopropyl)-1-piperazinyl-]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benz-o[h]-1,6-naphthyridin-2(1H)-one
Formula C₃₅H₂₈F₃N₅O₂
Permeability Cell-permeable
Molecular Weight 607.62 g/mol
CAS-No 1222998-36-8
Restrictions For Research Use only
Format Liquid
Buffer A 10 mM solution in DMSO
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 12 months
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