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  • 产品名称：Crizotinib

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  • 产品厂商：Biovision
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简单介绍：
Crizotinib
详情介绍：
Characteristics A specific, ATP-competitive, small-molecule inhibitor of the receptor tyrosine kinases (RTKs) c-Met and anaplastic lymphoma kinase (ALK). Iinhibits tyrosine phosphorylation of activated ALK at nanomolar concentrations. Inhibits the growth and survival of cell lines dependent upon c-Met or ALK enzymatic activity.
Purity ≥ 98 % by HPLC
Chemical Name 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
Formula C₂₁H₂₂Cl₂FN₅O
Permeability Cell-permeable
Molecular Weight 450.34 g/mol
CAS-No 877399-52-5
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
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image for Crizotinib (ABIN629338) Crizotinib