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  • 产品名称：Marimastat

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  • 产品厂商：Biovision
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Marimastat
详情介绍：
Characteristics A broad spectrum matrix metalloprotease (MMP) inhibitor with IC50 values of 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively. It covalently binds to the zinc(II) ion in the active site of MMPs, thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
Purity ≥ 98 % by HPLC
Chemical Name (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide; BB-2516; TA-2516; Marimistat
Formula C₁₅H₂₉N₃O₅
Permeability Cell-permeable
Molecular Weight 331.41 g/mol
CAS-No 154039-60-8
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 48 months
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image for Marimastat (ABIN629088) Marimastat