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  • 产品名称：Vandetanib

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  • 产品厂商：Biovision
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Vandetanib
详情介绍：
Characteristics A potent inhibitor of kinase insert domain-containing receptor [KDR/vascular endothelial growth factor receptor (VEGFR) 2] tyrosine kinase activity (IC50 = 40 nM). This compound also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC50 = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC50 = 500 nM) but shows selectivity relating to a range of other tyrosine and serine-threonine kinases.
Purity ≥ 98 % by HPLC
Chemical Name N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine; ZD6474, Zactima
Formula C₂₂H₂₄BrFN₄O₂
Permeability Cell-permeable
Molecular Weight 475.35 g/mol
CAS-No 443913-73-3
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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