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  • 产品名称：GANT58

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  • 产品厂商：Biovision
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简单介绍：
GANT58
详情介绍：
Characteristics Cell-permeable. Acts as a blocker of Hedgehog (Hh) pathway downstream of SMO and SUFU causing Gli1 nuclear accumulation. It also targets Gli-mediated gene transactivation (IC50 approx. 5 µM in SAG-stimulated Shh-L2 cells) and displays anti-proliferative and antitumor activity in vivo.
Purity ≥ 98 % by HPLC
Chemical Name 2,3,4,5-Tetra(4-pyridyl)thiophene; NSC75503
Formula C₂₄H₁₆N₄S
Permeability Cell-permeable
Molecular Weight 392.48 g/mol
CAS-No 64048-12-0
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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