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  • 产品名称：Niclosamide

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  • 产品厂商：Biovision
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简单介绍：
Niclosamide
详情介绍：
Characteristics A STAT3 signaling pathway inhibitor. Niclosamide potently inhibits the activation and transcriptional function of STAT3 and induces cell growth inhibition, apoptosis, and cell cycle arrest of cancer cells with constitutively active STAT3. Also reversibly inhibits mTORC1 signaling and stimulates autophagy in vitro, displays antineoplastic effects in acute myelogenous leukemia (AML) stem cells.
Purity ≥ 98 % by HPLC
Chemical Name 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
Formula C₁₃H₈Cl₂N₂O₄
Permeability Cell-permeable
Molecular Weight 327.12 g/mol
CAS-No 50-65-7
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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