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  • 产品名称：FludarabinePhosphate

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  • 产品厂商：Biovision
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FludarabinePhosphate
详情介绍：
Characteristics A chemotherapy drug used in the treatment of hematological malignancies. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase-beta, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.
Purity ≥ 98 %
Chemical Name [(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)- 3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid; Fludara
Formula C₁₀H₁₃FN₅O₇P
Permeability Not-permeable
Molecular Weight 365.21 g/mol
CAS-No 75607-67-9
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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image for Fludarabine Phosphate (ABIN629041) Fludarabine Phosphate