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  • 产品名称：NSC23766

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  • 产品厂商：Biovision
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简单介绍：
NSC23766
详情介绍：
Characteristics Acell-permeable, reversible, and selective Rac1 inhibitor,inhibiting Rac1 activation by the Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam 1 (IC50 = 50 µM) without affecting the closely related GTPases, Cdc42, and RhoA activation. NSC 23766 has been used to investigate the role of Rac1 in such diverse cellular functions as stem cell mobilization, epithelial cell migration, angiogenesis, leukemia cell migration and growth, etc.
Purity ≥ 98 % by HPLC
Chemical Name N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
Formula C₂₄H₃₅N₇.3HCl
Permeability Cell-permeable
Molecular Weight 530.97 g/mol
CAS-No 733767-34-5
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for NSC 23766 (ABIN629350) NSC 23766