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  • 产品名称：Capecitabine

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  • 产品厂商：Biovision
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简单介绍：
Capecitabine
详情介绍：
Characteristics A pre-prodrug of 5-fluorouracil (5-FU). After oral uptake, capecitabine is first metabolized to 5'-deoxy-5-fluorocytidine (5'-DFCR), which occurs mainly in the liver by carboxyl-esterase. The metabolite is converted to 5'-deoxy-5-fluoro-uridine (5'-DFUR) by cytidine deaminase in liver and tumor tissue. Then 5'-DFUR is converted to 5-FU intracellularly by thymidine phosphorylase, which is often expressed in tumor tissue.
Purity ≥ 99 % by HPLC
Chemical Name Pentyl[1-(3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl)- 5-fluoro-2-oxo-1H-pyrimidin- 4-yl]aminomethanoate; captabin; Ro 09-1978; Xabine
Formula C₁₅H₂₂FN₃O₆
Permeability Cell-permeable
Molecular Weight 359.35 g/mol
CAS-No 154361-50-9
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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image for Capecitabine (ABIN629004) Capecitabine