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  • 产品名称:Piperlongumine

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简单介绍:
Piperlongumine
详情介绍:
Characteristics A constituent of the pepper Piper longum L. that selectively kills cancer cells but not normal cells. Piperlongumine increases the level of reactive oxygen species (ROS) and apoptotic cell death in both cancer cells and normal cells engineered to have a cancer genotype, irrespective of p53 status, but it has little effect on either rapidly or slowly dividing primary normal cells. Also potently inhibits the growth of spontaneously formed malignant breast tumors and their associated metastases in mice.
Purity ≥ 97 %
Chemical Name (E)-1-(3-(3,4,5-Trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one; 1-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2(1H)-one; Piplartine
Formula C₁₇H₁₉NO₅
Permeability Cell-permeable
Molecular Weight 317.34 g/mol
CAS-No 20069-09-4
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
Supplier Images
 image for Piperlongumine (ABIN629312) Piperlongumine